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Siegesbeckia Orientalis Extract

Siegesbeckia Orientalis Extract Siegesbeckia Orientalis Extract is obtained from the herb Siegesbeckia orientalis L. This herb has been used for centuries externally to soothe inflammation and stimulate wound healing, which it does through tissue regeneration by way of collagen matrix build-up.

A now expired patent by Pierre Fabre Medicaments describes its ability to stimulate wound healing, to promote more regular tissue renewal, to increase the normal appearance of scars and to fully restore elasticity to damaged skin with collagen fibers arranged in regular fashion.

Extracts of Siegesbeckia orientalis have shown anti-inflammatory properties, inhibition of collagenase and protection from UV induced erythema.

This initial research led to an investigation of Siegesbeckia Orientalis Extract ability to restructure stretch marks. Stretch marks are caused by abnormal stretching of the dermis (pregnancy, change in weight), from a linear scar or from some endocrine disorders. In each case the stretch mark affects the elastin fibers in the middle dermis, which are diminished or disappear. Any effective treatment for stretch marks thus must restore normal quantities of collagen and elastin fibers.

The effects shown in a four-week clinical study where a crème containing 1.5% of Siegesbeckia Orientalis Extract was applied by volunteers twice daily are listed below.


Length of Streaks Reduced 52.15%
Surface Smoothness Increased 13.7%
Indented Surfaces Reduced 55.4%
Length of Irregularities Reduced 52.2%

These results correspond to restructuring of the tissue. At the end of treatment the surface of the skin was more regular in appearance and the global profile was more uniform with stretch marks tending to fade.

These results show Siegesbeckia Orientalis Extract to possess exciting characteristics for the treatment of stretch marks. In addition, Siegesbeckia Orientalis Extract is shown to possess excellent tolerance and non-toxicity.